Article

Functional and Physical Interaction between p53 and BZLF1: Implications for Epstein-Barr Virus Latency

1994-03-01

Abstract excerpt

The p53 tumor suppressor protein, which is commonly mutated in human cancers, has been shown to interact directly with virally encoded from papillomavirus, adenovirus, and simian virus 40. The disruption of p53 function may be required for efficient replication of certain viruses and may also play a role in the development of virally induced malignancies. Infection with Epstein-Barr virus (EBV) has been associated...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ad860e8b-d1f5-5e54-a4e4-dc9b3cbf802c
DOI: 10.1128/mcb.14.3.1929-1938.1994

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Functional and Physical Interaction between p53 and BZLF1: Implications for Epstein-Barr Virus LatencyDOI 10.1128/mcb.14.3.1929-1938.1994Read

Functional and physical interaction between p53 and BZLF1: implications for Epstein-Barr virus latency.Semantic proximity Read

Transient increases in p53-responsible gene expression at early stages of Epstein-Barr virus productive replicationSemantic proximity Read

The Epstein-Barr Virus Immediate-Early Protein BZLF1 Regulates p53 Function through Multiple MechanismsSemantic proximity Read

Expression of Epstein–Barr virus BZLF1 immediate-early protein induces p53 degradation independent of MDM2, leading to repression of p53-mediated transcriptionSemantic proximity Read

Identification of a novel element involved in regulation of the lytic switch BZLF1 gene promoter of Epstein-Barr virus.Semantic proximity Read

ZEB1 regulates the latent-lytic switch in infection by Epstein-Barr virus.Semantic proximity Read

The B-Cell-Specific Transcription Factor and Master Regulator Pax5 Promotes Epstein-Barr Virus Latency by Negatively Regulating the Viral Immediate Early Protein BZLF1Semantic proximity Read

Functional Interaction between Epstein-Barr Virus Replication Protein Zta and Host DNA Damage Response Protein 53BP1Semantic proximity Read

Reactivation of Epstein-Barr virus: regulation and function of the BZLF1 geneSemantic proximity Read

Direct interaction of p53 with the Y-box binding protein,YB-1 : A mechanism for regulation of human gene expressionSemantic proximity Read

Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expressionSemantic proximity Read

Structure and function of the Epstein-Barr virus BZLF1 protein.Semantic proximity Read