Article

Downregulation of CCL22 and Mutation of NOTCH1 in Tongue Squamous Cell Carcinoma Decreases Th2 Cell Recruitment and Expression to Predict Poor Clinical Outcomes

2021-02-04

Abstract excerpt

<h4>Background: </h4> Tongue squamous cell carcinoma (TSCC) exhibits a high rate of local recurrence and cervical lymph node metastasis. The effect of the tumor microenvironment on TSCC remains unclear. <h4>Methods: </h4>: Transcriptome data and somatic mutation data of TSCC were obtained from the HNSC project of The Cancer Genome Atlas (TCGA). Immune filtration analysis between early stage (clinical stage I–II) a...

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Literature Corpus work: ad360342-f94c-587c-b464-5452d31ecd06
DOI: 10.21203/rs.3.rs-152215/v1

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