Article

Targeting UNC-51-like kinase 1 can inhibit esophageal cancer cell proliferation and regulate autophagy

2023-05-22

Abstract excerpt

The purpose of this study was to investigate the expression of UNC-51-like kinase 1 (ULK1) in esophageal cancer(ESCA) and its prognostic value, its effect on esophageal cancer cell growth and proliferation, and the synergistic effect of its inhibitor and cisplatin on esophageal cancer cells. <h4>Methods:</h4> 1. The expression and prognosis of ULK1 in pancancer and ESCA were analyzed with the TCGA database. 2. The...

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Literature Corpus work: ad288969-82d0-5196-8556-b53f7a8e82e8
DOI: 10.21203/rs.3.rs-2950135/v1

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