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Article

Practical Approaches for Whole-Genome Sequence Analysis of Heart- and Blood-Related Traits.

American journal of human genetics - 2 Feb 2017

Morrison Alanna C, Huang Zhuoyi, Yu Bing, Metcalf Ginger, Liu Xiaoming, Ballantyne Christie, Coresh Josef, Yu Fuli, Muzny Donna, Feofanova Elena, Rustagi Navin, Gibbs Richard, Boerwinkle Eric

Abstract excerpt

Whole-genome sequencing (WGS) allows for a comprehensive view of the sequence of the human genome. We present and apply integrated methodologic steps for interrogating WGS data to characterize the genetic architecture of 10 heart- and blood-related traits in a sample of 1,860 African Americans. In order to evaluate the contribution of regulatory and non-protein coding regions of the genome, we conducted aggregate...

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Identifiers

PMID: 28089252
DOI: 10.1016/j.ajhg.2016.12.009
PMCID: PMC5294677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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