Article

ERAP1, ERAP2, and two copies of HLA-Aw19 alleles increase the risk for Birdshot Chorioretinopathy in HLA-A29 carriers

2021-07-05

Abstract excerpt

<h4>Purpose</h4> Birdshot Chorioretinopathy (BSCR) is strongly associated with HLA-A29. This study was designed to elucidate the genetic modifiers of BSCR in HLA-A29 carriers. <h4>Methods</h4> We sequenced the largest BSCR cohort to date, including 286 cases and 108 HLA-A29 positive controls to perform genome wide common and rare variant associations. We further typed the HLA alleles of cases and 45,386 HLA-A29 co...

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Literature Corpus work: acf01e8b-dd0b-58fc-8edc-1bcbf65aa1da
DOI: 10.1101/2021.07.02.21259921

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ERAP1, ERAP2, and two copies of HLA-Aw19 alleles increase the risk for Birdshot Chorioretinopathy in HLA-A29 carriersDOI 10.1101/2021.07.02.21259921Read

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