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Novel <i>in vivo</i> measurement of muscle total carnitine concentration reveals potential mechanism linking mitochondrial dysfunction and lipid accumulation

2026-07-29

Abstract excerpt

Free carnitine is essential to mitochondrial health by buffering the free acetyl-CoA pool and thereby maintaining energy production. It is also responsible for transporting long-chain fatty acids into the mitochondria for oxidation. Almost all the body’s carnitine is in muscle, and plasma concentrations do not reflect tissue content, but there are as yet no non-invasive techniques to assess muscle total or free ca...

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Literature Corpus work
acdc44a1-9ce3-5262-8142-51c922c7b7a4
DOI
10.64898/2026.07.28.26359098
Open publication

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Novel <i>in vivo</i> measurement of muscle total carnitine concentration reveals potential mechanism linking mitochondrial dysfunction and lipid accumulationDOI 10.64898/2026.07.28.26359098
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