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A Prospective Observational Study to Assess the Impact of Pharmacogenetics on Outcomes in Vascular Surgery (PROSPER)

2024-05-24

Abstract excerpt

<h4>Introduction</h4> Patients with chronic limb threatening ischaemia (CLTI) are often prescribed clopidogrel in order to reduce their risk of major adverse limb and cardiovascular events. Clopidogrel is metabolised by the CYP2C19 enzyme, and genetics variations in CYP2C19 are common. These variants can influence an individual’s ability to metabolise clopidogrel to its active metabolite. This work aims to establi...

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Literature Corpus work
acabb514-9f56-5848-8fcc-7537f910590c
DOI
10.1101/2024.05.24.24307885
Open publication

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A Prospective Observational Study to Assess the Impact of Pharmacogenetics on Outcomes in Vascular Surgery (PROSPER)DOI 10.1101/2024.05.24.24307885
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