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Generation of an induced pluripotent stem cell line ERCi003-A derived from a patient with maturity-onset diabetes of the young type 10 caused by a heterozygous <i>INS</i> mutation

2024-12-05

Abstract excerpt

Maturity-onset diabetes of the young type 10 (MODY10) is inherited in an autosomal dominant manner, characterized by islet cell dysfunction, impaired insulin synthesis and secretion. MODY10 is relatively rare, and is caused by a mutation of the 11p15.5 site on chromosome 11 encoding insulin. We obtained iPSCs (ERCi003-A line) from dermal fibroblasts derived from a patient with MODY10 carrying a previously undescri...

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Literature Corpus work
ac8a107c-0f4b-5be4-bcd3-b748271324b7
DOI
10.1101/2024.12.04.626760
Open publication

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Generation of an induced pluripotent stem cell line ERCi003-A derived from a patient with maturity-onset diabetes of the young type 10 caused by a heterozygous <i>INS</i> mutationDOI 10.1101/2024.12.04.626760
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