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SARS-CoV-2 and MERS-CoV Share the Furin Site CGG-CGG Genetic Footprint

2021-10-14

Abstract excerpt

The SARS-CoV-2 polybasic furin cleavage site is still a missing link. Remarkably, the two arginine residues of this protease recognition site are encoded by the CGG codon, which is rare in Betacoronavirus. However, the arginine pair is common at viral furin cleavage sites, but are not CGG-CGG encoded. The question is: Is this genetic footprint unique to the SARS-CoV-2? To address the issue, using Perl scripts, her...

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Literature Corpus work
ac82dd70-2c35-5523-b60a-6bd8590f27a2
DOI
10.20944/preprints202110.0080.v2
Open publication

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