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Article

Reinterpreting I2 Thresholds: Toward Context-Specific Heterogeneity Assessment in Evidence Synthesis

2026-02-28

Abstract excerpt

<h4>Background: </h4> The Cochrane Handbook’s I 2 categorization system (0-25% ”low”, 25-75% ”moderate”, ≥50% ”high” heterogeneity) serves as the international standard for interpreting heterogeneity in meta-analysis, influencing thousands of systematic reviews annually. Despite its ubiquitous adoption, neither the logical coherence nor the intended analytical function of this system has been systematically exami...

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Literature Corpus work
8fe78056-19d2-5beb-bf38-cecdc0e68a1c
DOI
10.22541/au.177226210.01680055/v1
Open publication

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Reinterpreting I2 Thresholds: Toward Context-Specific Heterogeneity Assessment in Evidence SynthesisDOI 10.22541/au.177226210.01680055/v1
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