Article

Simplified Molecular Classification of Lung Adenocarcinomas Based on <i>EGFR</i> , <i>KRAS</i> , and <i>TP53</i> Mutations

2019-01-21

Abstract excerpt

<h4>Introduction</h4> Gene expression profiling has consistently identified three molecular subtypes of lung adenocarcinoma that have prognostic implications. To facilitate stratification of patients with this disease into similar molecular subtypes, we developed and validated a simple, mutually exclusive classification. <h4>Methods</h4> Mutational status of EGFR , KRAS , and TP53 was used to define six mutua...

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Literature Corpus work: ac307894-11c0-5a21-93fc-6a5d106f2cc4
DOI: 10.1101/525949

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