Article

Function expansion of antitumor transcriptional activator NFE2L1 by the original discovery of its non-transcription factor activity

2020-10-08

Abstract excerpt

<h4>ABSTRACT</h4> Antitumor transcription activator NFE2L1, with the functions to regulate redox homeostasis, protein turnover, and material metabolism, plays an important role in embryonic development and specialization of tissue and organ functions. Deficiency of NFE2L1 gene in different regions yields distinct phenotypes, suggesting that NFE2L1 may have a transcription factor-independent function. Here we ori...

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Literature Corpus work: ac2e82ef-03f2-5404-9d8d-cb62f2013ea4
DOI: 10.1101/2020.10.08.330597

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