Article

Therapeutic Distance: An Orbit-Based Framework for ICU Decision Support Initial Validation in 11,627 Sepsis Patients from MIMIC-IV

2026-04-04

Abstract excerpt

<h4>Background</h4> Patient matching in intensive care databases yields sample sizes too small for individualised outcome analysis. Current AI systems provide population-level guideline summaries but omit stratification variables that may invert therapy signals at the individual level. <h4>Methods</h4> We developed the Therapeutic Distance framework, which computes the z-standardised distance between a patient’s...

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Literature Corpus work: ac1f113b-abf7-5f6c-9c9c-5ce6815164a4
DOI: 10.64898/2026.04.02.26350049

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