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Target Trial Emulation of Early versus Delayed Renal Replacement Therapy in Sepsis-Associated AKI: A Causal Inference Study

2026-05-25

Abstract excerpt

<title>Abstract</title> <p>Background The optimal timing of continuous renal replacement therapy (CRRT) in sepsis-associated acute kidney injury (SA-AKI) remains intensely debated. Landmark randomized controlled trials have yielded discordant results, yet the optimal timing for the vulnerable SA-AKI subphenotype remains unclear. Methods To emulate a target trial using causal inference methods to estimate the ef...

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Literature Corpus work
0a350477-53ee-5674-bad6-39c88dcc255d
DOI
10.21203/rs.3.rs-9628328/v1
Open publication

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Target Trial Emulation of Early versus Delayed Renal Replacement Therapy in Sepsis-Associated AKI: A Causal Inference StudyDOI 10.21203/rs.3.rs-9628328/v1
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