Article

Non-Monotone Exponential Time (NEXT) Model for the Longitudinal Trend of a Continuous Outcome in Clinical Trials

2023-06-07

Abstract excerpt

<title>Abstract</title> <p>The dose response curve has been studied extensively for decades. However, most of these methods ignore intermediate measurements of the response variable and only use the measurement at the endpoint. In early phase trials, it is crucial to utilize all available data due to the smaller sample size. Simulation studies have shown that the longitudinal dose-response surface model provides...

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Literature Corpus work: abf23eef-25cc-5ab7-85dd-e9f5965508dd
DOI: 10.21203/rs.3.rs-2907717/v1

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