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Evaluating the Therapeutic Effects of Amino Acid Treatment on Vaso-Occlusive Pain in Sickle Cell Disease: A Systematic Review and Meta-Analysis Protocol

2024-08-14

Abstract excerpt

2 <h4>Introduction</h4> Sickle Cell Disease (SCD) affects over 100,000 individuals in the United States and 20 million globally, causing acute and chronic pain. The disease is characterized by misshapen red blood cells caused by mutations in beta-hemoglobin genes. SCD leads to multiorgan damage, chronic anemia, and severe pain crises, with a median life expectancy of 43 years. Current treatments involve opioids, b...

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Literature Corpus work
abcdab99-6ad6-5fe4-b0be-b18df40899fa
DOI
10.1101/2024.08.08.24311691
Open publication

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