Article

Cholinergic signals promote esophageal squamous cell carcinoma metastasis by activating EGFR/AKT signaling pathway

2022-05-23

Abstract excerpt

<h4>Purpose: </h4> Increasing evidence has shown that the nervous system plays a vital role in the regulation of tumorigenesis. However, the regulatory mechanism of the parasympathetic nervous system in the progression of esophageal squamous cell carcinoma (ESCC) has not been elucidated. <h4>Methods: </h4> Vesicular acetylcholine transporter (VAChT) protein expression was detected by immunohistochemistry (IHC) and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ab5e2236-0519-505e-ad45-c50eb34a4353
DOI: 10.21203/rs.3.rs-1534161/v3

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cholinergic signals promote esophageal squamous cell carcinoma metastasis by activating EGFR/AKT signaling pathwayDOI 10.21203/rs.3.rs-1534161/v3Read

The Role of the Autonomic Nervous System in Oncogenesis: Friend or Foe?Semantic proximity Read

Cholinergic receptors as target for cancer therapy in a systems medicine perspective.Semantic proximity Read

Tumor Neurobiology and the War of Nerves in CancerSemantic proximity Read

The nerve cells in gastrointestinal cancers: from molecular mechanisms to clinical interventionSemantic proximity Read

Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer StemnessSemantic proximity Read

Sympathetic innervation induced by nerve growth factor promotes malignant transformation in gastric cancerSemantic proximity Read

Cancer-nervous system crosstalk: from biological mechanism to therapeutic opportunitiesSemantic proximity Read

Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic SignalingSemantic proximity Read

Cancer-induced Nerve Injury Unveils a Sympathetic-to-Sensory Nerve Axis in Head and Neck CancerSemantic proximity Read

Indirect cholinergic activation slows down pancreatic cancer growth and tumor-associated inflammationSemantic proximity Read

Alterations in Esophageal MicroRNAs Expression in Primary Esophageal Achalasia by Next-Generation SequencingSemantic proximity Read

The cholinergic system and cancerSemantic proximity Read