Article

Stable reference genes for 24-hour circadian profiling of core clock genes in the blood of obstructive sleep apnea patients

2025-09-22

Abstract excerpt

Obstructive sleep apnea (OSA), one of the most common breathing disorders during sleep, is associated with circadian rhythm disruption, yet circadian genes expressed in blood remain largely unexplored as biomarkers. Reliable circadian gene expression analysis requires stable reference genes for qRT-PCR normalization, but no clear guidance exists for blood-based circadian studies in OSA. We evaluated the expression...

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Literature Corpus work: ab42ffad-7aec-5037-aebd-ee832d76bf6c
DOI: 10.1101/2025.09.22.677736

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