Article

Reference Genes for Circadian Profiling of Core Clock Genes in the Blood of Obstructive Sleep Apnea Patients

2026-06-11

Abstract excerpt

Circadian rhythm disruptions are increasingly recognized in disorders such as obstructive sleep apnea (OSA), yet analysis of 24-hour gene expression patterns remains challenging due to the lack of reliable reference genes for normalization. Even commonly used housekeeping genes may exhibit circadian oscillations, which can confound rhythmic gene expression analyses and hinder biomarker identification. To address t...

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Literature Corpus work: c94f7731-a52e-5c57-b1c3-ec366496f097
DOI: 10.20944/preprints202606.0800.v1

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