Article

Enrichment of disease-associated genes in cortical areas defined by transcriptome-based parcellation

2020-03-03

Abstract excerpt

The parcellation of the cerebral cortex serves the investigation of the emergence of uniquely human brain functions and disorders. We employed hierarchical clustering based on comprehensive transcriptomic data of the human cortex in order to delineate areas with distinct gene expression profiles. These profiles were analyzed for the enrichment of gene sets associated with brain disorders by genome-wide studies (GW...

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Literature Corpus work: ab18d09d-6be5-51b9-9656-377b73d6d12a
DOI: 10.1101/2020.03.02.971911

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