Article

An interaction-based model for neuropsychiatric features of copy-number variants

2018-11-02

Abstract excerpt

<h4>ABSTRACT</h4> Variably expressive copy-number variants (CNVs) are characterized by extensive phenotypic heterogeneity of neuropsychiatric phenotypes. Approaches to identify single causative genes for these phenotypes within each CNV have not been successful. Here, we posit using multiple lines of evidence, including pathogenicity metrics, functional assays of model organisms, and gene expression data, that mu...

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Literature Corpus work: aac7730a-e9c4-5869-b342-25fa7ecb6c04
DOI: 10.1101/459958

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