Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Somatic copy number variants in neuropsychiatric disorders.

Current opinion in genetics & development - 1 Jun 2021

Maury Eduardo A, Walsh Christopher A

Abstract excerpt

Copy number variants (CNVs) have been implicated in neuropsychiatric disorders, with rare-inherited and de novo CNVs (dnCNVs) having large effects on disease liability. Recent studies started exploring a class of dnCNVs that occur post-zygotically, and are therefore present in some but not all cells of the body. Analogous to conditional mutations in animal models, the presence of risk mutations in a fraction of...

Topics

Brain Diseases
DNA Copy Number Variations
Genetic Predisposition to Disease
Genome-Wide Association Study
Genomics
Humans
Mental Disorders
Mutation
Risk Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open in PubMed Open full text

Identifiers

PMID: 33444936
DOI: 10.1016/j.gde.2020.12.013
PMCID: PMC8205940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic copy number variants in neuropsychiatric disorders.PMID 33444936Read ↗

Copy Number Variations in Neuropsychiatric Disorders.Semantic proximity Read ↗

Copy number variation and neuropsychiatric illness.Semantic proximity Read ↗

Copy number variation and psychiatric disease risk.Semantic proximity Read ↗

Mechanisms of copy number variants in neuropsychiatric disorders: From genes to therapeutics.Semantic proximity Read ↗

Genomic structural variation in psychiatric disorders.Semantic proximity Read ↗

CNVs: harbingers of a rare variant revolution in psychiatric genetics.Semantic proximity Read ↗

Implications of germline copy-number variations in psychiatric disorders: review of large-scale genetic studies.Semantic proximity Read ↗

Gene copy number variation and common human disease.Semantic proximity Read ↗

Human copy number variation and complex genetic disease.Semantic proximity Read ↗

Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders.Semantic proximity Read ↗

Genomic mosaicism in the developing and adult brainSemantic proximity Read ↗

Population-based Risk of Psychiatric Disorders Associated with Recurrent CNVsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.