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Article

Somatic copy number variants in neuropsychiatric disorders.

Current opinion in genetics & development - 1 Jun 2021

Maury Eduardo A, Walsh Christopher A

Abstract excerpt

Copy number variants (CNVs) have been implicated in neuropsychiatric disorders, with rare-inherited and de novo CNVs (dnCNVs) having large effects on disease liability. Recent studies started exploring a class of dnCNVs that occur post-zygotically, and are therefore present in some but not all cells of the body. Analogous to conditional mutations in animal models, the presence of risk mutations in a fraction of...

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Identifiers

PMID: 33444936
DOI: 10.1016/j.gde.2020.12.013
PMCID: PMC8205940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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