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Structural and functional analysis of pyocin S8 from Pseudomonas aeruginosa : requirement of a glutamate in the H-N-H motif for the DNase activity

2020-05-01

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Multi-drug resistance (MDR) is a serious threat to global public health, making the development of new antimicrobials an urgent necessity. Pyocins are protein antibiotics produced by Pseudomonas aeruginosa strains to kill closely related cells during intraspecific competition. Here, we report an in depth biochemical, microbicidal and structural characterization of a new S-type pyocin, named S8. Initially, we desc...

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Literature Corpus work: aac32069-e211-5981-9ff8-9e6a36a8491c
DOI: 10.1101/2020.04.29.068437

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Structural and functional analysis of pyocin S8 from Pseudomonas aeruginosa : requirement of a glutamate in the H-N-H motif for the DNase activityDOI 10.1101/2020.04.29.068437Read

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Structural and functional analysis of pyocin S8 from <i>Pseudomonas aeruginosa</i> : requirement of a glutamate in the H-N-H motif for the DNase activity

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