Article
Detecting SARS-CoV-2 variants with SNP genotyping.
PloS one - 1 Jan 2021
Harper Helen, Burridge Amanda, Winfield Mark, Finn Adam, Davidson Andrew, Matthews David, Hutchings Stephanie, Vipond Barry, Jain Nisha, Edwards Keith, Barker Gary
Abstract excerpt
Tracking genetic variations from positive SARS-CoV-2 samples yields crucial information about the number of variants circulating in an outbreak and the possible lines of transmission but sequencing every positive SARS-CoV-2 sample would be prohibitively costly for population-scale test and trace operations. Genotyping is a rapid, high-throughput and low-cost alternative for screening positive SARS-CoV-2 samples...
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