Article

Stress attenuation by the adrenergic-specific lncRNA NESPR prevents cell death in neuroblastoma cells

2025-04-11

Abstract excerpt

<h4>ABSTRACT</h4> Neuroblastoma is a pediatric cancer of the sympathetic nervous system characterized by heterogeneous cell states that mirror normal differentiation trajectories. Each state is governed by a core regulatory transcriptional circuitry that reinforces cell identity through an autoregulatory feedforward loop. We identified the long non-coding RNA NESPR as specifically expressed in adrenergic neurobla...

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Literature Corpus work: aa7c493f-8949-5e62-81c1-13b27eac57fe
DOI: 10.1101/2025.04.07.647560

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