Article

Genetic analysis of functional rare germline variants across 9 cancer types from the DiscovEHR study

2019-12-12

Abstract excerpt

Rare variants play an essential role in the etiology of cancer and characterizing rare germline variants that impact the risk of cancer is an ongoing challenge. We performed a genome-wide rare variant analysis using germline whole exome sequencing (WES) data derived from the Geisinger MyCode initiative to discover cancer predisposition variants. The case-control association analysis was conducted by binning pathog...

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Literature Corpus work: aa3872b9-0108-50d3-9263-e44fa1706a7e
DOI: 10.1101/2019.12.09.19013334

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