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Identification of transcriptome-wide cobalt chloride-induced hypoxia-responsive long noncoding RNAs regulated by cytoplasmic mRNA capping enzyme

2024-11-21

Abstract excerpt

Long non-coding RNAs (lncRNAs) are key regulators of gene expression in human cancers, influencing tumor microenvironment (TME). Hypoxia, a hallmark of solid tumors, elevates hypoxia-inducible factor 1α (HIF-1α), which regulates hypoxia-responsive lncRNAs (HRLs). These HRLs are essential in regulating gene expression under hypoxic conditions at both transcriptional and post-transcriptional levels. However, the mec...

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Literature Corpus work
a9971ea7-b629-52a2-bdc0-c108e83ade51
DOI
10.1101/2024.11.21.624636
Open publication

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Identification of transcriptome-wide cobalt chloride-induced hypoxia-responsive long noncoding RNAs regulated by cytoplasmic mRNA capping enzymeDOI 10.1101/2024.11.21.624636
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