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Article

Polarized RPE Secretome Preserves Photoreceptors in Retinal Dystrophic RCS Rats

22 Jun 2023

Abstract excerpt

Retinal degenerative diseases, including age-related macular degeneration (AMD) and retinitis pigmentosa, lack effective therapies. Conventional monotherapeutic approaches fail to target the multiple affected pathways in retinal degeneration. However, the retinal pigment epithelium (RPE) secretes several neurotrophic factors addressing diverse cellular pathways, potentially preserving photoreceptors. This study...

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Share to Photoreceptor and optogenetics research
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37443724
DOI: 10.3390/cells12131689

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