Article

Genetic Polymorphisms of SLC22A1 and CYP2C9 Genes in Patients with Type 2 Diabetes in Port Harcourt, Nigeria

2026-08-26

Abstract excerpt

Background: Genetic variation in proteins involved in antidiabetic drug transport and metabolism may contribute to differences in type 2 diabetes mellitus (T2D) susceptibility and treatment response. Aim: To determine the genotype and allele distributions of selected CYP2C9 (rs1057910, rs1799853, rs41291560, rs9332214) and SLC22A1 (rs1220835, rs594709, rs622342) variants and to evaluate their associations with T2D...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a8d8a353-01f2-5048-b1bf-e4ec1f0b5bf9
DOI: 10.9734/ajbge/2026/v9i2197

Open publication

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Click a neighbor to travelStep 1 · 12 closest

Genetic Polymorphisms of SLC22A1 and CYP2C9 Genes in Patients with Type 2 Diabetes in Port Harcourt, NigeriaDOI 10.9734/ajbge/2026/v9i2197Read

Pharmacogenetic studies update in type 2 diabetes mellitusSemantic proximity Read

Implications of Genetic Elements on Type 2 Diabetes Mellitus Pathogenesis and Management.Semantic proximity Read

Impact of SLC22A1 variants rs622342 and rs72552763 on HbA1c and metformin plasmatic concentration levels in patients with type 2 diabetes mellitusSemantic proximity Read

Influence of SLC22A1 rs622342 genetic polymorphism on metformin response in South Indian type 2 diabetes mellitus patientsSemantic proximity Read

Pharmacogenetics and personalized treatment of type 2 diabetesSemantic proximity Read

Association of SLC11A1 polymorphisms with anthropometric and biochemical parameters describing Type 2 Diabetes Mellitus.Semantic proximity Read

Metformin Pharmacogenetics: Effects of SLC22A1, SLC22A2, and SLC22A3 Polymorphisms on Glycemic Control and HbA1c LevelsSemantic proximity Read

Clinical Study on the Relationship between the SNP rs8192675 (C/C) Site of SLC2A2 Gene and the Hypoglycemic Effect of Metformin in Type 2 Diabetes.Semantic proximity Read

The Effect of Genetic Variants of SLC22A2 (rs662301 and rs315978) on the response to Metformin in type 2 Saudi diabetic patients.Semantic proximity Read

Analysis of the Potential Association of Drug-Metabolizing Enzymes CYP2C9*3 and CYP2C19*3 Gene Variations With Type 2 Diabetes: A Case-Control Study.Semantic proximity Read

ABCC8 genetic variants and risk of diabetes mellitus.Semantic proximity Read

Association of CDKAL1 RS10946398 Gene Polymorphism with Susceptibility to Diabetes Mellitus Type 2: A Meta-Analysis.Semantic proximity Read