Article

M2 macrophage-derived exosomal long noncoding RNA Myt1l promotes lung metastasis of pancreatic cancer cells via the miR-135/Slug axis

2023-08-10

Abstract excerpt

<title>Abstract</title> <p>Purpose Long non-coding RNAs (lncRNAs) in exosomes are important mediators of communication between tumor cells and their microenvironment. Previous studies have found that M2 macrophages promote the migration and invasion of pancreatic cancer (PC) cells through epithelial-mesenchymal transition (EMT). The aim of this study was to elucidate how M2 macrophage-derived exosomal lncRNAs pr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a8cacfb1-fee7-5c5b-89f3-74123def96e7
DOI: 10.21203/rs.3.rs-3239578/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

M2 macrophage-derived exosomal long noncoding RNA Myt1l promotes lung metastasis of pancreatic cancer cells via the miR-135/Slug axisDOI 10.21203/rs.3.rs-3239578/v1Read

MiR-1301-3p Inhibits Epithelial to Mesenchymal Transition via Targeting RhoA in Pancreatic CancerSemantic proximity Read

microRNA signature for human pancreatic cancer invasion and metastasisSemantic proximity Read

Pancreatic cancer-derived exosomal miR-510 promotes macrophage M2 polarization and facilitates cancer cell aggressive phenotypes.Semantic proximity Read

Long non-coding RNAs: Emerging regulators of invasion and metastasis in pancreatic cancerSemantic proximity Read

In vitro and in vivo evaluation of anti-tumoral effect of M1 phenotype induction in macrophages by miR-130 and miR-33 containing exosomes.Semantic proximity Read

Characterizing the role of exosomal miRNAs in metastasisSemantic proximity Read

MiR-1301-3p Inhibits Epithelial-mesenchymal Transition via Targeting RhoA in Pancreatic CancerSemantic proximity Read

Role of exosomal microRNA-125b-5p in conferring the metastatic phenotype among pancreatic cancer cells with different potential of metastasis.Semantic proximity Read

β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axisSemantic proximity Read

The long non-coding RNA EGOT promotes pancreatic cancer progression by sequestering miR-214 to derepress PLS3 expressionSemantic proximity Read

LUAD BALF Exosomal miR-183-5p promoted the metastasis of NLCSCSemantic proximity Read

M2 macrophage-derived exosomal microRNAs inhibit cell migration and invasion in gliomas through PI3K/AKT/mTOR signaling pathwaySemantic proximity Read