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Article

Role of exosomal microRNA-125b-5p in conferring the metastatic phenotype among pancreatic cancer cells with different potential of metastasis.

Life sciences - 15 Aug 2020

Wu Mengwei, Tan Xiaodong, Liu Peng, Yang Yifan, Huang Yinpeng, Liu Xinlu, Meng Xiangli, Yu Boqiang, Wu Yunhao, Jin Haoyi

Abstract excerpt

AIMS: To explore the pro-metastatic role of exosomes derived from highly invasive pancreatic cancer cell and the associated aberrant expression of exosomal microRNAs (miRNAs). MAIN METHODS: Weakly invasive PC-1 cells were treated with exosomes of highly invasive PC-1.0 cells to determine the pro-metastatic effect of PC-1.0 derived exosomes. The exosomal miRNA profile was further investigated using high-throughput...

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Identifiers

PMID: 32470446
DOI: 10.1016/j.lfs.2020.117857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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