Article

Review of the Fluoropyrimidine Antidote Uridine Triacetate

2024-09-02

Abstract excerpt

not-yet-known not-yet-known not-yet-known unknown In 2015, the United States Food and Drug Administration (FDA) approved uridine triacetate to treat overdose and severe toxicity of the fluoropyrimidine chemotherapy agents 5-fluorouracil (5-FU) and its oral prodrug capecitabine. Uridine triacetate is as an oral prodrug of uridine which competes with cytotoxic fluoropyrimidine metabolites for incorporation into...

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Literature Corpus work: a8aa8b44-b917-5a46-afe8-5875f1986ee5
DOI: 10.22541/au.172526739.97846727/v1

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