Article

Novel DNA methylation changes in mouse lungs associated with heavy smoking

2023-11-06

Abstract excerpt

<h4>ABSTRACT</h4> Smoking is a potent cause of asthma, chronic obstructive pulmonary disease (COPD) and many other health defects, and changes in DNA methylation (DNAm) have been identified as a potential link between smoking and these health outcomes. However, most links between smoking and DNAm have been made using blood and other easily accessible tissues in humans, while evidence from more directly affected t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a8734390-42ae-5427-a39d-ec8a126bf797
DOI: 10.1101/2023.11.06.565206

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Novel DNA methylation changes in mouse lungs associated with heavy smokingDOI 10.1101/2023.11.06.565206Read

Early life exposure to cigarette smoke primes lung function and DNA methylation changes at <i>Cyp1a1</i> upon exposure later in lifeSemantic proximity Read

Lung DNA Methylation in Chronic Obstructive Pulmonary Disease: Relationship with Smoking Status and Airflow Limitation SeveritySemantic proximity Read

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression.Semantic proximity Read

Role of epigenetic mechanisms in the pathogenesis of chronic respiratory diseases and response to inhaled exposures: From basic concepts to clinical applicationsSemantic proximity Read

Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigeneticsSemantic proximity Read

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPDSemantic proximity Read

Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic healthSemantic proximity Read

Smoking-Associated Site-Specific Differential Methylation in Buccal Mucosa in the COPDGene StudySemantic proximity Read

DNA Methylation Is Globally Disrupted and Associated with Expression Changes in Chronic Obstructive Pulmonary Disease Small AirwaysSemantic proximity Read

DNA methylation profiling in peripheral lung tissues of smokers and patients with COPDSemantic proximity Read

The molecular impact of cigarette smoking resembles aging across tissuesSemantic proximity Read

Epigenetic Control of Gene Expression in the LungSemantic proximity Read