Article

Copy number variants in BRCA1 and BRCA2 genes in Polish patients with breast and ovarian cancer

2026-04-27

Abstract excerpt

<title>Abstract</title> <p> Purpose: <italic>BRCA1</italic> and <italic>BRCA2</italic> are key susceptibility genes in hereditary breast and ovarian cancer (HBOC), with mutational status guiding PARP inhibitor therapy. While single-nucleotide variants (SNVs) predominate, the prevalence of copy number variants (CNVs) varies significantly across different populations. This study aims to determine the incidence...

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Literature Corpus work: a833204b-aad8-5cd3-9fb8-43f35beac851
DOI: 10.21203/rs.3.rs-9336936/v1

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