Article
Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci.
Journal of the National Cancer Institute - 14 Nov 2022
DeVries Amber A, Dennis Joe, Tyrer Jonathan P, Peng Pei-Chen, Coetzee Simon G, Reyes Alberto L, Plummer Jasmine T, Davis Brian D, Chen Stephanie S, Dezem Felipe Segato, Aben Katja K H, Anton-Culver Hoda, Antonenkova Natalia N, Beckmann Matthias W, Beeghly-Fadiel Alicia, Berchuck Andrew, Bogdanova Natalia V, Bogdanova-Markov Nadja, Brenton James D, Butzow Ralf, Campbell Ian, Chang-Claude Jenny, Chenevix-Trench Georgia, Cook Linda S, DeFazio Anna, Doherty Jennifer A, Dörk Thilo, Eccles Diana M, Eliassen A Heather, Fasching Peter A, Fortner Renée T, Giles Graham G, Goode Ellen L, Goodman Marc T, Gronwald Jacek, Håkansson Niclas, Hildebrandt Michelle A T, Huff Chad, Huntsman David G, Jensen Allan, Kar Siddhartha, Karlan Beth Y, Khusnutdinova Elza K, Kiemeney Lambertus A, Kjaer Susanne K, Kupryjanczyk Jolanta, Labrie Marilyne, Lambrechts Diether, Le Nhu D, Lubiński Jan, May Taymaa, Menon Usha, Milne Roger L, Modugno Francesmary, Monteiro Alvaro N, Moysich Kirsten B, Odunsi Kunle, Olsson Håkan, Pearce Celeste L, Pejovic Tanja, Ramus Susan J, Riboli Elio, Riggan Marjorie J, Romieu Isabelle, Sandler Dale P, Schildkraut Joellen M, Setiawan V Wendy, Sieh Weiva, Song Honglin, Sutphen Rebecca, Terry Kathryn L, Thompson Pamela J, Titus Linda, Tworoger Shelley S, Van Nieuwenhuysen Els, Edwards Digna Velez, Webb Penelope M, Wentzensen Nicolas, Whittemore Alice S, Wolk Alicja, Wu Anna H, Ziogas Argyrios, Freedman Matthew L, Lawrenson Kate, Pharoah Paul D P, Easton Douglas F, Gayther Simon A, Jones Michelle R
Abstract excerpt
BACKGROUND: Known risk alleles for epithelial ovarian cancer (EOC) account for approximately 40% of the heritability for EOC. Copy number variants (CNVs) have not been investigated as EOC risk alleles in a large population cohort. METHODS: Single nucleotide polymorphism array data from 13 071 EOC cases and 17 306 controls of White European ancestry were used to identify CNVs associated with EOC risk using a rare...
