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A Gene-expression Module Identifies Circulating Immune Cells with Enhanced Recruitment to Sites of Inflammation

2023-04-12

Abstract excerpt

Circulating immune cells are critical mediators of inflammation upon recruitment to tissues, yet how their gene expression state influences this recruitment is not well understood. Here, we report longitudinal single-cell transcriptome profiling of peripheral blood mononuclear cells in patients undergoing kidney transplantation rejection. We identify a novel gene expression module, termed ALARM (early activation t...

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Literature Corpus work
a7fe228e-3644-5552-bd9a-dea74ccbab1a
DOI
10.1101/2023.04.11.536347
Open publication

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A Gene-expression Module Identifies Circulating Immune Cells with Enhanced Recruitment to Sites of InflammationDOI 10.1101/2023.04.11.536347
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