Article

The <i>Pax6</i> master control gene initiates spontaneous retinal development via a self-organising Turing network

2019-03-21

Abstract excerpt

Understanding how complex organ systems are assembled from simple embryonic tissues is a major challenge. Across the animal kingdom a great diversity of visual organs are initiated by a ‘master control gene’ called Pax6 , which is both necessary and sufficient for eye development 1–6 . Yet precisely how Pax6 achieves this deeply homologous function is poorly understood. Here we show that vertebrate Pax6 intera...

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Literature Corpus work: a7a865bb-5840-5b32-968d-f27e27d74d1f
DOI: 10.1101/583807

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