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Article

Origins of the Embryo: Self-organization through cybernetic regulation.

Bio Systems - 1 Nov 2018

Stone Robert, Portegys Tom, Mikhailovsky George, Alicea Bradly

Abstract excerpt

The construction of an embryo from a single cell precursor is a highly complex process. Evolutionary emergence of the first embryos is even more complex, and involves both a transition to multicellularity along with the establishment of developmental mechanisms. We propose that embryogenesis relies on a community of cells conforming to a regulatory model of emergent multicellularity. This model draws together...

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PMID: 30134151
DOI: 10.1016/j.biosystems.2018.08.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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