Article

The Effects of United Kingdom SARS-CoV-2 Spike Mutations on Spike-ACE2 Interactions Studied by Using Molecular Dynamic Simulation

2023-10-18

Abstract excerpt

A newly emergent betacoronavirus, SARS-CoV-2, is a tremendous threat globally and causing severe acute respiratory syndrome coronavirus-2, a big pandemic introduced worldwide in 2019. Trimeric spike glycoprotein (S) is on the viral membrane envelope that serves as the machinery to fuse the viral and host cell membranes by binding to a cellular receptor, ACE2. In the United Kingdom, a SARS-CoV-2 variant has been id...

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Literature Corpus work: a7a0c09b-48dc-54c2-b40e-e5e0c335977b
DOI: 10.2139/ssrn.4601580

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