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Article

N439K variant in spike protein may alter the infection efficiency and antigenicity of SARS-CoV-2 based on molecular dynamics simulation

2020-11-23

Abstract excerpt

<h4>ABSTRACT</h4> Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing an outbreak of coronavirus disease 2019 (COVID-19), has been undergoing various mutations. The analysis of the structural and energetic effects of mutations on protein-protein interactions between the receptor binding domain (RBD) of SARS-CoV-2 and angiotensin converting enzyme 2 (ACE2) or neutralizing monoclonal antibodies wi...

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Literature Corpus work
5858e62d-98ab-5135-a9d9-13c9f6879be6
DOI
10.1101/2020.11.21.392407
Open publication

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N439K variant in spike protein may alter the infection efficiency and antigenicity of SARS-CoV-2 based on molecular dynamics simulationDOI 10.1101/2020.11.21.392407
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