Article

Role of m6A modification in stromal and immune activation patterns together with response to ICI in melanoma

2022-02-25

Abstract excerpt

<h4>Background: </h4> Great progress has been made in understanding the epigenetic regulation of the immune response. However, the influence of RNA N6-methyladenosine (m6A) regulation on the tumor microenvironment (TME) of melanoma is still unknown. Methods We comprehensively evaluated 790 samples of melanoma based on 21 m6A regulator genes and associated these regulators with infiltration characteristics in the...

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Literature Corpus work: 7a02d571-7790-5d2e-a975-42c74a22455e
DOI: 10.21203/rs.3.rs-1363616/v1

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