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Article

Hypomethylation of CD3D promoter induces immune cell infiltration and supports malignant phenotypes in uveal melanoma.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2023

Zhang Chao, Wu Shuai

Abstract excerpt

Alterations in DNA methylation in malignant diseases have been heralded as promising targets for diagnostic, prognostic, and predictive values. This study was based on epigenetic alterations and immune cell infiltration analysis to investigate the mechanism of CD3D methylation in uveal melanoma (UM). Bioinformatics analysis was performed on transcriptome data, 450 K methylation data, and clinical information of...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Identifiers

PMID: 37651092
DOI: 10.1096/fj.202300505RR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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