Article
iLEC-DNA: Identifying Long Extra-chromosomal Circular DNA by Fusing Sequence-derived Features of Physicochemical Properties and Nucleotide Distribution Patterns
2023-09-29
Abstract excerpt
Long extrachromosomal circular DNA (leccDNA) regulates several biological processes such as genomic instability, gene amplification, and oncogenesis. The identification of leccDNA holds significant importance to investigate its potential associations with cancer, autoimmune, cardiovascular, and neurological diseases. In addition, understanding these associations can provide valuable insights about disease mechanis...
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Identifiers and source
- Literature Corpus work
- a7648dcc-532a-55fe-a695-ea543d78f90b
- DOI
- 10.21203/rs.3.rs-3368586/v1