Article

ZERO-INFLATED NEGATIVE BINOMIAL REGRESSION FOR DIFFERENTIAL ABUNDANCE TESTING IN MICROBIOME STUDIES

2021-03-05

Abstract excerpt

Motivation: The human microbiome plays an important role in human health and disease. The composition of the human microbiome is influenced by multiple factors and understanding these factors is critical to elucidate the role of the microbiome in health and disease and for development of new diagnostics or therapeutic targets based on the microbiome. 16S ribosomal RNA (rRNA) gene targeted amplicon sequencing is a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a727b31f-f257-5de1-8d9c-6a0a305aef56
DOI: 10.18454/jbg.2016.2.2.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ZERO-INFLATED NEGATIVE BINOMIAL REGRESSION FOR DIFFERENTIAL ABUNDANCE TESTING IN MICROBIOME STUDIESDOI 10.18454/jbg.2016.2.2.1Read

Association of Body Index with Fecal Microbiome in Children Cohorts with Ethnic-Geographic Factor Interaction: Accurately Using a Bayesian Zero-inflated Negative Binomial Regression ModelSemantic proximity Read

CAFT: A Compositional Log-Linear Model for Microbiome Data with Zero CellsSemantic proximity Read

Joint modeling of zero-inflated longitudinal proportions and time-to-event data with application to a gut microbiome studySemantic proximity Read

Negative binomial mixed models for analyzing microbiome count dataSemantic proximity Read

Generalized Estimating Equation Modeling on Correlated Microbiome Sequencing Data with Longitudinal MeasuresSemantic proximity Read

metamicrobiomeR: an R package for analysis of microbiome relative abundance data using zero-inflated beta GAMLSS and meta-analysis across studies using random effect modelsSemantic proximity Read

Zero-inflated Bayesian factor analysis model with skew-normal priors for modeling microbiome dataSemantic proximity Read

A realistic benchmark for the identification of differentially abundant taxa in (confounded) human microbiome studiesSemantic proximity Read

Exact Tests of Zero Variance Component in Presence of Multiple Variance Components with Application to Longitudinal Microbiome StudySemantic proximity Read

Multivariable Association Discovery in Population-scale Meta-omics StudiesSemantic proximity Read

Negative Binomial factor regression with application to microbiome data analysisSemantic proximity Read

Bias-mitigated microbiome inference refines coronary artery disease signatureSemantic proximity Read