Article

Exact Tests of Zero Variance Component in Presence of Multiple Variance Components with Application to Longitudinal Microbiome Study

2018-03-13

Abstract excerpt

<h4>Summary</h4> In the metagenomics studies, testing the association of microbiome composition and clinical conditions translates to testing the nullity of variance components. Computationally efficient score tests have been the major tools. But they can only apply to the null hypothesis with a single variance component and when sample sizes are large. Therefore, they are not applicable to longitudinal microbiom...

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Literature Corpus work: 98906823-fcea-5f02-867f-c2e0cbbd62f7
DOI: 10.1101/281246

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