Article

metamicrobiomeR: an R package for analysis of microbiome relative abundance data using zero-inflated beta GAMLSS and meta-analysis across studies using random effect models

2018-04-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The rapid growth of high-throughput sequencing-based microbiome profiling has yielded tremendous insights into human health and physiology. Data generated from high-throughput sequencing of 16S rRNA gene amplicons are often preprocessed into composition or relative abundance. However, reproducibility has been lacking due to the myriad of different experimental and computatio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1c1ed133-f481-5f2b-8a17-5af81695105a
DOI: 10.1101/294678

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

metamicrobiomeR: an R package for analysis of microbiome relative abundance data using zero-inflated beta GAMLSS and meta-analysis across studies using random effect modelsDOI 10.1101/294678Read

Association of Body Index with Fecal Microbiome in Children Cohorts with Ethnic-Geographic Factor Interaction: Accurately Using a Bayesian Zero-inflated Negative Binomial Regression ModelSemantic proximity Read

Comparison of the effectiveness of different normalization methods for metagenomic cross-study phenotype prediction under heterogeneitySemantic proximity Read

Comparison of the effectiveness of different normalization methods for metagenomic cross-study phenotype prediction under heterogeneity.Semantic proximity Read

Generalized Estimating Equation Modeling on Correlated Microbiome Sequencing Data with Longitudinal MeasuresSemantic proximity Read

Human Microbiome Mixture Analysis using Weighted Quantile Sum RegressionSemantic proximity Read

mbDriver: identifying driver microbes in microbial communities based on time-series microbiome dataSemantic proximity Read

Multivariable Association Discovery in Population-scale Meta-omics StudiesSemantic proximity Read

MIDASim: a fast and simple simulator for realistic microbiome dataSemantic proximity Read

Joint modeling of zero-inflated longitudinal proportions and time-to-event data with application to a gut microbiome studySemantic proximity Read

Zero-inflated Bayesian factor analysis model with skew-normal priors for modeling microbiome dataSemantic proximity Read

An Exponential Scale Mixture Model for Metatranscriptomics Data with Application to Inflammatory Bowel DiseaseSemantic proximity Read

Statistical normalization methods in microbiome data with application to microbiome cancer researchSemantic proximity Read