Article

RNA‐Binding Proteins MCPIP3 and IGF2BP3 Antagonize Lung Cancer Metastasis by Reversibly Regulating METAP2 Expression via mRNA Stability

2026-06-09

Abstract excerpt

<h4>Background: </h4> /Objectives: The homeostatic imbalance between tumor metastasis-promoting genes and -suppressing genes determines the metastatic potential of lung adenocarcinoma (LUAD) cells. However, the post-transcriptional regulation mechanism mediated by RNA-binding proteins (RBPs) in maintaining the expression balance of tumor metastasis-related genes remains unclear. <h4>Methods:</h4> The expression of...

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Literature Corpus work: a711ec22-20de-567d-916c-13e69401329d
DOI: 10.20944/preprints202606.0695.v1

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