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CPEB3-mediated MTDH mRNA translational suppression restrains hepatocellular carcinoma progression

23 Sept 2020

Abstract excerpt

Cytoplasmic polyadenylation element-binding protein 3 (CPEB3) is a sequence-specific RNA-binding protein. We had reported that CPEB3 is involved in hepatocellular carcinoma (HCC) progression. However, the underlying mechanisms of CPEB3 in HCC remain unclear. In this study, we firstly performed RNA immunoprecipitation to uncover the transcriptome-wide CPEB3-bound mRNAs (CPEB3 binder) in HCC. Bioinformatic analysis...

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PMID: 32968053
DOI: 10.1038/s41419-020-02984-y

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