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IGF2BP3 Promotes Lung Cancer Progression Through FTO Dependent m6A Modification by Stabilizing N-myc

2020-12-29

Abstract excerpt

<h4>Background: </h4> N6-methyladenosine modification has been involved in various biological processes. However, its role in non-small cell lung cancer has not been well studied. Here, we show that IGF2BP3, as an transcription factor, plays a critical oncogenic role in non-small-cell lung cancer carcinogenesis through activating FTO expression and inducing aberrant m6A modification. <h4>Methods: </h4>: To evaluat...

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Literature Corpus work
86e4ce5f-d72c-5f8e-899d-f9602dfc87af
DOI
10.21203/rs.3.rs-135593/v1
Open publication

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IGF2BP3 Promotes Lung Cancer Progression Through FTO Dependent m6A Modification by Stabilizing N-mycDOI 10.21203/rs.3.rs-135593/v1
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