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Article

Functional characterization of snoRNA-derived RNA (sdRNA) expression in healthy hematopoiesis and acute myeloid leukemia

2026-01-14

Abstract excerpt

<title>Abstract</title> <p>SnoRNAs are highly expressed in AML and play a role in leukemogenesis and leukemic maintenance. SnoRNAs can be further processed into snoRNA-derived RNAs (sdRNAs). Expression and implications of sdRNAs in AML and healthy hematopoiesis, however, remain largely elusive. We characterized sdRNA and snoRNA levels in hematopoietic stem cells (HSCs), healthy peripheral blood cells, and 159 AML...

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Literature Corpus work
a6f35a5c-ce37-5d32-9d16-662da06b9549
DOI
10.21203/rs.3.rs-8423046/v1
Open publication

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Functional characterization of snoRNA-derived RNA (sdRNA) expression in healthy hematopoiesis and acute myeloid leukemiaDOI 10.21203/rs.3.rs-8423046/v1
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